![]() ![]() Some may have symptoms of ARIA such as headache, dizziness, nausea, confusion and vision changes. Some people may also have small spots of bleeding in or on the surface of the brain with the swelling, although most people with swelling in areas of the brain do not have symptoms. It is typically a temporary swelling in areas of the brain that usually resolves over time. ARIA is a common side effect that does not usually cause symptoms but can be serious. Another potentially serious side effect is allergic reaction. The most common side effects include amyloid-related imaging abnormalities (ARIA), headache and fall. Aducanumab needs to be given by IV in order for the medication to reach the brain most effectively.Īccess to aducanumab is limited, as is Medicaid coverage of the drug. Infusion can be done at hospitals or infusion therapy centers. How is this drug administered?Īducanumab is administered intravenously (IV) via a 45- to 60-minute infusion every 4 weeks. If you or a loved one is experiencing memory changes, the Alzheimer’s Association strongly encourages speaking with a health care provider for a thorough evaluation and diagnosis. Download How do I receive this treatment? It is important to learn as much as you can about which drugs are available. There is exciting progress in Alzheimer’s and dementia research that is creating promising new treatments. This means that a physician should confirm the presence of beta-amyloid plaques in the brain before prescribing this anti-amyloid plaque treatment.Ĭonfirmatory tests like cerebrospinal fluid analysis or amyloid PET imaging should be a part of the diagnostic process to determine eligibility for the treatment. However, the label says aducanumab is indicated for the treatment of Alzheimer’s, based on reduction in beta-amyloid plaques, one of the hallmarks of the disease. The FDA is not requiring any specific diagnostic test. What type of diagnostic test is the FDA requiring? There is no evidence that aducanumab can restore lost memories or cognitive function. ![]() Will this drug restore memories or cognitive function that has been lost? Its removal may also help other processes in your brain to operate more efficiently. The brain goes on creating beta-amyloid, but aducanumab decreases the amount. How does aducanumab work?Īducanumab is designed to target and remove specific forms of beta-amyloid that accumulate into plaques, which may contribute to cell death and tissue loss in areas of the brain particularly important for memory, thinking, learning and behaviors. ![]() There is no safety or effectiveness data on initiating treatment at earlier or later stages of the disease than were studied. Treatment with aducanumab may be appropriate for people in the disease stage studied in the clinical trials. The drug was studied in people living with early Alzheimer’s disease - which includes people with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease who also have evidence of a buildup of amyloid plaques in the brain. Download Who should take this drug?Īducanumab is indicated for the treatment of Alzheimer’s disease. Effective communication with care team members - particularly health care providers - is critical to ensure that the person living with dementia receives the best possible care.
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